"In early 2012, Connelly put aside his research on the Cold War and began studying US secrecy policy. He learned everything he could about how federal records are created, maintained, and released to the public. He learned that since the 1970s, the government’s budget for reviewing and declassifying sensitive documents had failed to keep pace with the production of new ones. The backlog of secrets had grown significantly following the September 11, 2001, attacks, when federal employees were instructed to be more cautious in deciding whether to release old documents. After Barack Obama became president, the glut shrank a bit, as government censors were told to relax their standards. By the end of Obama’s first term, though, progress plateaued and the size of the backlog stabilized at about 360 million pages. Then Connelly had an idea: could he use data mining to infer what types of information were being left out of the public record?"
"It has been known for a while that maintenance of the stem-cell pluripotent state is regulated by a small number of key genes—about 20. But how they were linked together remained a mystery, and a complex one at that. There are literally billions of possible ways to combine them. The scientists and researchers analyzed correlations between the genes and created a meta-model of the network, using techniques used to identify software bugs and guarantee program correctness—particularly in safety-critical systems—to distill the connections that result in observed stem-cell behaviors."