When I first got Quicksilver I thought it was neat, but didn't totally understand the whole "our app will change your life" rhetoric around it. Well, today I'm here at my Atlantic desk (I've mostly been at home) using the office Mac and I'm punching away at some keys like an idiot wondering why the program isn't launching. Maybe I need to hit the key-combination harder, I think. And then it hits me -- no Quicksilver.

Also indispensible (and relevant to PC users) -- Pandora.