Bet On Colorado
The Red Sox were only seven games better than the Rockies over the course of the regular season, a nearly-meaningless edge when you're talking about a seven-game playoff series. In the second half of the season, they were considerably worse. In the postseason, they've gone 7-3; the Rockies have gone 7-0. Admittedly, the National League offers markedly inferior competition, and I do think the Red Sox are a better team than the Colorado. But 2-1 favorites? Not hardly.
(All betting lines provided for informational purposes only.)