For weeks, Americans looked on as other countries grappled with case reports of rare, sometimes fatal blood abnormalities among those who had received the AstraZeneca vaccine against COVID-19. That vaccine has not yet been authorized by the FDA, so restrictions on its use throughout Europe did not get that much attention in the United States. But Americans experienced a rude awakening this week when public-health officials called for a pause on the use of the Johnson & Johnson vaccine, after a few cases of the same, unusual blood-clotting syndrome turned up among the millions of people in the country who have received it.

The world is now engaged in a vaccination program unlike anything we have seen in our lifetimes, and with it, unprecedented scrutiny of ultra-rare but dangerous side effects. An estimated 852 million COVID-19 vaccine doses have been administered across 154 countries, according to data collected by Bloomberg. Last week, the European Medicines Agency, which regulates medicines in the European Union, concluded that the unusual clotting events were indeed a side effect of the AstraZeneca vaccine; by that point, more than 220 cases of dangerous blood abnormalities had been identified. Only half a dozen cases have been documented so far among Americans vaccinated with the Johnson & Johnson vaccine, and a causal link has not yet been established. But the latest news suggests that the scope of this problem might be changing.

Last week, the CDC acknowledged what many of us have been saying for almost nine months about cleaning surfaces to prevent transmission by touch of the coronavirus: It’s pure hygiene theater.

“Based on available epidemiological data and studies of environmental transmission factors,” the CDC concluded, “surface transmission is not the main route by which SARS-CoV-2 spreads, and the risk is considered to be low.” In other words: You can put away the bleach, cancel your recurring Amazon subscription for disinfectant wipes, and stop punishing every square inch of classroom floor, restaurant table, and train seat with high-tech antimicrobial blasts. COVID-19 is airborne: It spreads through tiny aerosolized droplets that linger in the air in unventilated spaces. Touching stuff just doesn’t carry much risk, and more people should say so, very loudly.

Illustrations by Leonardo Santamaria

This article was published online on April 15, 2021.

The Motel El Encanto in Hermosillo, Mexico, served a lavish breakfast that John and Andra Patterson liked to eat on the tiled deck near their suite. The couple would discuss the day ahead over fresh pineapple and pan dulces while their 4-year-old daughter, Julia, watched the gray cat that skulked about the motel’s Spanish arches.

On the morning of March 22, 1974, the Pattersons’ breakfast chatter centered on their search for a permanent home. They were nearing their two-month anniversary of living in Hermosillo, where John was a junior diplomat at the American consulate, and the motel was feeling cramped.

After breakfast, Andra dropped John off at work. Because this was his first posting as a member of the United States Foreign Service, the 31-year-old Patterson had been given an unglamorous job: He was a vice consul responsible for promoting trade between the U.S. and Mexico, which on this particular Friday meant driving out to meet with a group of ranchers who hoped to improve their yield of beef.

Photo illustrations by Oliver Munday and Arsh Raziuddin; renderings by Justin Metz

This article was published online on March 11, 2021.

Updated at 7:42 p.m. ET on March 26, 2021.

Dalton is one of the most selective private schools in Manhattan, in part because it knows the answer to an important question: What do hedge-funders want?

They want what no one else has. At Dalton, that means an “archaeologist in residence,” a teaching kitchen, a rooftop greenhouse, and a theater proscenium lovingly restored after it was “destroyed by a previous renovation.”

“Next it’ll be a heliport,” said a member of the local land-use committee after the school’s most recent remodel, which added two floors—and 12,000 square feet—to one of its four buildings, in order to better prepare students “for the exciting world they will inherit.” Today Dalton; tomorrow the world itself.

The Johnson & Johnson shot is teetering on the precipice of becoming America’s “dudes only” vaccine. On Tuesday, the CDC and FDA advised halting the vaccine’s nationwide rollout to investigate six cases of a rare blood-clotting disorder that’s occurred in people within about two weeks of receiving the vaccine—all of them women under the age of 50. In an emergency meeting convened Wednesday by the CDC, experts raised the possibility of limiting its future use to males, reserving Johnson & Johnson’s vaccine, as some have unfortunately put it, for johnsons alone.

That idea, crude though it may be, has something to it. The demographic pattern that’s emerged is striking, and many of the experts I talked with this week told me they suspect that, if the vaccine is ultimately linked to these clots, the relationship will come with a clear-cut sex or gender difference too. (These questions are also being debated with regard to the AstraZeneca vaccine, which contains comparable ingredients and might very rarely cause a similar or identical type of clotting disorder.)

Each installment of “The Friendship Files” features a conversation between The Atlantic’s Julie Beck and two or more friends, exploring the history and significance of their relationship.

This week she talks with Judie, an introvert, and Kristi, an extrovert, about their opposites-attract friendship, and how Judie leaned on it when her daughter was diagnosed with cancer during the pandemic. They discuss their years as roommates, how “Auntie Kristi” is an important part of Judie’s daughters’ lives, and how Kristi showed up for Judie and her daughters when they desperately needed support in a time of social distance.

The Friends:

Kristi Dusek, 45, a project manager at a research nonprofit, who lives in Baltimore
Judie Hyun, 45, the chief of the division of infectious-disease surveillance for the Maryland Department of Health, who lives in Baltimore

The president was insistent as he left office: “We’re not going anywhere.” It had been a turbulent end of the presidency—impeachment, appalling pardons, and a lengthy dispute over the outcome of the presidential election—but he knew that he had a devoted following, and he had every intention to remain a force in politics. And not just him: His family was eager to cash in on his electoral success, too. Usually a former president laid low for a while after leaving office. He wasn’t going to do that. He’d remain a political force, and the dominant figure in his party.

But the plan didn’t go well. The president sat at his new home—he had decamped from his longtime home state—guzzling Diet Cokes and calling friends to rage about how unfairly he’d been treated and complain about overzealous prosecutors. “You get tired of listening to it,” one friend confessed.

In early March 2020, Rick Phillips, 63, and his wife, Sheryl Phillips, quietly cloistered themselves in their Indianapolis home. They swore off markets, movie theaters, the gym, and, hardest of all, visits with their three young grandchildren. This April, three weeks after receiving her second shot of Pfizer’s vaccine, Sheryl broke her social fast and walked into a grocery store for the first time since last spring. Rick has yet to join her. He received his shots on the same days his wife received hers. By official standards, he, too, can count himself as fully vaccinated. But he feels that he cannot act as though he is. “I personally remain scared to death,” he told me.

Rick has rheumatoid arthritis, which once rendered him “barely able to walk across the room,” he said. He now treats the condition with an intensely immunosuppressive drug that strips his body of the ability to churn out disease-fighting antibodies. Rick credits the treatment with changing his life. But it might also keep him from developing lasting defenses against COVID-19.

On February 25, I got my first shot of the Pfizer vaccine bright and early, picked up a breakfast burrito on the walk home, and spent the rest of the day sitting in my desk chair, doing what can only be described as vibing. I felt a little bit stoned, like I had taken a low-grade edible instead of being shot up with cutting-edge technology that would help end a year-long global disaster. This acute, mildly high feeling—“brain fog,” a known side effect of the vaccines—lasted about two days. As potential side effects go, it was rad.

More durable, though, was the strange feeling that began when I made my appointment. In the hours after scheduling my shot, I blew a deadline and was late to meet up with friends for a very cold outdoor hang. I was overcome with relief, everything felt slightly unreal, and the time-dependent obligations of my life faded to the periphery of my consciousness. In the two months since, the delirium has settled into something duller, less frantic—the keys are in the ignition, but my mind simply will not turn over.

Updated at 5:57 p.m. ET on January 14, 2020.

On a recent Saturday afternoon, I stood with my 13-year-old son in a long line stretching over the West Side Highway, cars careening below us. He was waiting to take an entrance exam for a specialized high school, a sacred moment, and yet I kept glancing at my phone to check the time. I had to meet my mother to tour an apartment because my childhood home in the East Village had burned down the week prior—a month after my father was diagnosed with late-stage lung cancer. My parents, who are in their 70s, were too overwhelmed to handle the logistics of finding a sublet on their own. On that day, and just about every day these past few months, I had to choose between caring for one family member or another. With so many crises under way, caring for myself hasn’t really been on the table.