Imagine it’s 2026. A man shows up in an emergency room, wheezing. He’s got pneumonia, and it’s hitting him hard. He tells one of the doctors that he had COVID-19 a few years earlier, in late 2021. He had refused to get vaccinated, and ended up contracting the coronavirus months after most people got their shots. Why did he refuse? Something about politics, or pushing back on government control, or a post he saw on Facebook. He doesn’t really remember. His lungs do, though: By the end of the day, he’s on a ventilator.

You’ll pay for that man’s decisions. So will I. We all will—in insurance premiums, if he has a plan with your provider, or in tax dollars, if the emergency room he goes to is in a public hospital. The vaccine refusers could cost us billions. Maybe more, over the next few decades, with all the complications they could develop. And we can’t do anything about it except hope that more people get their shots than those who say they will right now.

Every so often, an emerging technology changes the global balance of power, alters alliances, and shifts the relationships among nations. After World War II, nuclear weapons overthrew all of the existing geopolitical paradigms. The countries that got the bomb were considered global powers; countries that did not have it sought it, so that they could be considered powerful too.

Now a different technology is shifting global politics: the coronavirus vaccines—or, quite possibly, vaccines more broadly. Unlike nuclear weapons, vaccines don’t have the potential to end life on Earth, and their production and distribution will never require rigid rules to limit who gets them. Indeed, the international institutions being created to govern vaccine distribution are designed to promote proliferation, not restrict it. Nevertheless, global politics will be shaped by the vaccines, as will domestic politics in some countries, and in ways that might outlast this particular pandemic.

The Trump presidency may be over, but the Trump era has only just begun—at least when it comes to influence over the nation’s courts. Measured solely by the number of judges he appointed, Donald Trump’s impact is staggering: 234 judges, including 54 powerful appellate judges, almost one out of every three. By comparison, President Barack Obama appointed 172 judges (30 of them appellate) in his first term, while George W. Bush managed 204 (35 appellate). But Trump will have an even greater influence than this measurement suggests. That is because his judges won’t reach the apogee of their power until the early 2040s, when Trump-appointed chief judges are on track to simultaneously sit atop nearly every appeals court in the country.

For this month’s look-back at “Dear Therapist” columns, I’ve decided to turn not to a specific theme, but to a handful of columns that have been reader favorites over the years.

Rereading them, I understand why. Though the topics they cover are disparate—among them the loneliness of singledom, the shame brought on by abuse, the difficulties of extended family—each does something that I think of as typical Lori: providing readers (and the letter writers themselves) with a whole new framework for thinking about a problem.

One letter, to a woman who has a troubled relationship with her sister-in-law, stands out to me as paradigmatic. “Unfortunately, I can’t stand her,” the letter writer says. “Everything about her rubs me the wrong way. She sees the world in black and white, while I see infinite shades of gray.” How should she build a relationship with someone she so detests?

Here’s a cool trick for blowing any American’s mind. Tell us that in France, so many boulangeries shut down for vacation every summer that it can be tough to snag a baguette. Bakers aren’t the only ones who get time off. In August, up to half of the country’s salaried employees have been known to take at least a full week off from work. Half!

Americans are good at lots of different things, but going on vacation is not one of them. Every year in parts of Europe, summer turns into a mini-sabbatical. In Norway, during the tradition of fellesferie, the nation simply shuts down for a few weeks of July fun. In Italy, so many people take the last two weeks of August off that Rome’s transit system runs on a reduced “festivi” schedule. Meanwhile, guess which industrialized country is the only one that doesn’t guarantee time off to its workers? Guess which country left 768 million vacation days on the table in 2018? Guess which country … arghhhhhhhh.

In August 2011, Mitt Romney was campaigning for president at the Iowa State Fair and explaining why he didn’t want to raise taxes on the American people when a heckler shouted that corporations should pay a greater share of taxes.

“Corporations are people, my friend,” Romney replied. He was jeered in the crowd, and jeered even more by Democrats afterward. “I don’t care how many times you try to explain it,” Barack Obama said on the stump. “Corporations aren’t people. People are people.”

Ten years later, there’s been a strange inversion. Corporations, responding to pressure from Democrats, are acting more like people—using their clout to weigh in on legislation and social-justice issues that don’t immediately affect their taxes or bottom line. Republicans, meanwhile, are furious at the idea that companies might act this way.

Adapted from Rock Me on the Water, HarperCollins Publishers, 2021.

When CBS first placed All in the Family on the air, on January 12, 1971, it irrevocably transformed television. After a shaky first season in which it struggled to find an audience, the show prospered, rising to become No. 1 in the ratings for five consecutive years, a record unmatched at the time. All in the Family commanded national attention to a degree almost impossible to imagine in today’s fractionated entertainment landscape. Archie Bunker’s catchwords—stifle, meathead, and dingbat—all became national shorthand. Scholars earnestly debated whether the show punctured or promoted bigotry.

Its success not only helped lift The Mary Tyler Moore Show, M*A*S*H, and the other great topical comedies of the early 1970s, but also cemented the idea that television could be used to comment meaningfully on the society around it—an idea the networks had uniformly rejected throughout all the upheaval of the 1960s. That legacy—the determination to connect the medium to the moment—reverberates through shows as diverse as Fleabag, Atlanta, Breaking Bad, The Wire, and countless others. The night that CBS initially aired All in the Family was the first step on the road toward the Peak TV that we are living through today.

The crinkly form of a small, dried octopus lay on a desk in Washington, D.C., 170 years ago. The curious cephalopod, which had been collected more than 7,000 kilometers away in Brazil, was one of thousands of creatures obtained by researchers on the United States South Seas Exploring Expedition, which had taken explorers, navy men, merchants, and scientists on an epic voyage around the Pacific Ocean. The project took years, and some preserved specimens—including a few small-headed red octopuses with white, leopard-like spots that had been picked up from a fish market in Rio de Janeiro, and from local fishers—eventually wound up with experts, such as American naturalist Augustus Addison Gould, for scientific analysis.

A few weeks ago, Reuven went to a party. It was indoors. No one wore masks. No one who attended was in any rush to get a vaccine. Reuven and his wife were uncomfortable. But if they hadn’t gone, his relatives would have felt as if he were “judging them” for gathering, “and they judge me back,” he told me. “I have to weigh my options.” Reuven’s parents and siblings roll their eyes when he constantly talks about their risk of getting sick, just as he did at the beginning of the pandemic. He’s meshige far corona, they say. Crazy about the virus.

The Yiddish-speaking, Hasidic Jewish world that Reuven inhabits is intensely communal. Men crowd into synagogues in his Brooklyn neighborhood to pray together three times a day—morning, afternoon, and night. Many large families share small apartments or rowhouses, where they stage elaborate meals each week on Shabbat and during the Jewish calendar’s many holidays, filling their homes with scrambling kids and occasionally the cousins and uncles who live just blocks away. Orthodox Jews in New York are distinctly vulnerable to the virus for many of the same reasons low-income Black and Latino neighborhoods have been hit hard: crowded living spaces, lack of public-health infrastructure, jobs that require in-person work. For many people in these communities, sealing themselves inside their apartments for a year simply wasn’t possible. Reuven knows this; he doesn’t fault the Hasidim for the way they live. “We shouldn't be judged merely on the fact that we feel that some forms of gatherings are important to us, even during a pandemic,” he told me. “What’s so disappointing and depressing, and even shocking, is the fact that we chose to do all this with zero precautions, for which there is absolutely no excuse.”

Across the United States, cases have started rising again. In a few cities, even hospitalizations are ticking up. The twists and turns of a pandemic can be hard to predict, but this most recent increase was almost inevitable: A more transmissible and more deadly variant called B.1.1.7 has established itself at the precise moment when many regions are opening up rapidly by lifting mask mandates, indoor-gathering restrictions, and occupancy limits on gyms and restaurants.

We appear to be entering our fourth surge.

The good news is that this one is different. We now have an unparalleled supply of astonishingly efficacious vaccines being administered at an incredible clip. If we act quickly, this surge could be merely a blip for the United States. But if we move too slowly, more people will become infected by this terrible new variant, which is acutely dangerous to those who are not yet vaccinated.