december 2012

Updated at 10:36 a.m. ET on August 5, 2020.

There’s a joke about immunology, which Jessica Metcalf of Princeton recently told me. An immunologist and a cardiologist are kidnapped. The kidnappers threaten to shoot one of them, but promise to spare whoever has made the greater contribution to humanity. The cardiologist says, “Well, I’ve identified drugs that have saved the lives of millions of people.” Impressed, the kidnappers turn to the immunologist. “What have you done?” they ask. The immunologist says, “The thing is, the immune system is very complicated …” And the cardiologist says, “Just shoot me now.”

The thing is, the immune system is very complicated. Arguably the most complex part of the human body outside the brain, it’s an absurdly intricate network of cells and molecules that protect us from dangerous viruses and other microbes. These components summon, amplify, rile, calm, and transform one another: Picture a thousand Rube Goldberg machines, some of which are aggressively smashing things to pieces. Now imagine that their components are labeled with what looks like a string of highly secure passwords: CD8+, IL-1β, IFN-γ. Immunology confuses even biology professors who aren’t immunologists—hence Metcalf’s joke.

In March, tens of millions of American workers—mostly in white-collar industries such as tech, finance, and media—were thrust into a sudden, chaotic experiment in working from home. Four months later, the experiment isn’t close to ending. For many, the test run is looking more like the long run.

Google announced in July that its roughly 200,000 employees will continue to work from home until at least next summer. Mark Zuckerberg has said he expects half of Facebook’s workforce to be remote within the decade. Twitter has told staff they can stay home permanently.

With corporate giants welcoming far-flung workforces, real-estate markets in the superstar cities that combine high-paid work and high-cost housing are in turmoil. In the San Francisco Bay Area, rents are tumbling. In New York City, offices are still empty; so many well-heeled families with second homes have abandoned Manhattan that it’s causing headaches for the census.

Famous people want the world to know that Ellen DeGeneres is nice to famous people. Addressing media reports alleging a culture of harassment and bullying at DeGeneres’s talk show, the singer Katy Perry tweeted Tuesday that she’s “only ever had positive takeaways from my time with Ellen.” Ashton Kutcher, Kevin Hart, Jay Leno, Diane Keaton, and the superstar agent Scooter Braun have all recently made similar declarations about DeGeneres’s kindness, so as to push back against claims painting her as callous toward staffers, fans, and other entertainment-industry figures. “Looking forward to the future where we get back to loving one another,” Hart wrote, blasting those who have criticized DeGeneres and called for her to step down. “This hate shit has to stop.”

How did it come to this? A virus a thousand times smaller than a dust mote has humbled and humiliated the planet’s most powerful nation. America has failed to protect its people, leaving them with illness and financial ruin. It has lost its status as a global leader. It has careened between inaction and ineptitude. The breadth and magnitude of its errors are difficult, in the moment, to truly fathom.

In the first half of 2020, SARS‑CoV‑2—the new coronavirus behind the disease COVID‑19—infected 10  million people around the world and killed about half a million.

The coronavirus that causes COVID-19 has sickened more than 16.5 million people across six continents. It is raging in countries that never contained the virus. It is resurging in many of the ones that did. If there was ever a time when this coronavirus could be contained, it has probably passed. One outcome is now looking almost certain: This virus is never going away.

The coronavirus is simply too widespread and too transmissible. The most likely scenario, experts say, is that the pandemic ends at some point—because enough people have been either infected or vaccinated—but the virus continues to circulate in lower levels around the globe. Cases will wax and wane over time. Outbreaks will pop up here and there. Even when a much-anticipated vaccine arrives, it is likely to only suppress but never completely eradicate the virus. (For context, consider that vaccines exist for more than a dozen human viruses but only one, smallpox, has ever been eradicated from the planet, and that took 15 years of immense global coordination.) We will probably be living with this virus for the rest of our lives.