october 1870

This article contains spoilers for the series finale of Game of Thrones.

It went, roughly, like this: The queen who had sold herself as a reformer and a savior revealed herself to be, in the final countdown, the opposite. Airborne and seated on her dragon, Daenerys looked down at the populace of King’s Landing, at all those people caught in the crosshairs of political intrigue. She heard the bells, their clangs making clear that the city had surrendered. She gave a snarl of rage, and then, acting either on a cruel whim or on a cruel martial assessment—Daenerys’s thought process was one of many mysteries this season that Game of Thrones’ writers kept gallingly vague—she opened fire. The queen wielded her weapon, and the people below her burned.

Every week for the eighth and final season of Game of Thrones, three Atlantic staffers have been discussing new episodes of the HBO drama. Because no screeners were made available to critics in advance this year, we’ll be posting our thoughts on the series finale in installments.

Along the highways of states where support for abortion is at its lowest, it’s not uncommon to see road signs that say “choose adoption” and similar messages. The signs capture a preferred anti-abortion retort to outcries over abortion restrictions, like the kind Georgia and Alabama just passed: Women with unwanted pregnancies should find adoptive families.

Adoption is a choice certain women who don’t wish to keep their babies enter into happily. Some women find abortion to be anathema and rule it out among their options for an unwanted pregnancy. And for women considering abortion who ultimately settle on adoption, the process often benefits everyone involved.

Of course, adoption is not a reasonable option for all pregnant women. Some girls and women would imperil their health if they carried a baby to term. Many pro-abortion-rights people believe it is immoral to compel a woman to carry a pregnancy she does not want, especially if that pregnancy is a result of rape or incest. And some studies show that abortion is medically safer than childbirth.

It would have been easy to miss the stories late last week, what with a trade war in progress, a hot war with Iran threatened, and the president accusing his critics of treason.

But on Thursday, a report from the Government Accountability Office concluded that Ben Carson, the secretary of housing and urban development, broke the law in lavishly re-furnishing his office. The same day, the inspector general of the Environmental Protection Agency said that former Administrator Scott Pruitt wasted nearly $124,000 of taxpayer money on excessive travel, including first-class airline tickets.

For the first year and a half of the Trump administration, the petty corruption of Donald Trump’s aides was a leading story. During the spring and summer of 2018, there seemed to be nearly daily revelations about abuses at one department or another, from tony travel to soundproof booths. Then the issue sank from the headlines, for a variety of reasons. There were bigger stories, especially as Special Counsel Robert Mueller’s probe began producing more indictments. Pruitt was finally forced to resign, which seemed to tie a bow on the corruption thread. Besides, a certain numbness sets in after so many cases of wasted money.

Cancer cells grow in distinctive patterns that defy normal limitations.

That growth activity requires energy, and so, cancer cells metabolize nutrients in different ways from the healthy cells around them. In attempt to kill the tumor without killing the normally functioning cells, chemotherapy drugs target these pathways inside of cancer cells. This is notoriously difficult, expensive, and prone to toxic side effects that account for much of the suffering associated with the disease.

Now, doctors are starting to think more about specific nutrients that feed tumor cells. That is, how what we eat affects how cancers grow—and whether or not there are ways to potentially “starve” cancer cells without leaving a person undernourished, or even hungry.

The fight began with little subtlety. White, wealthy parents in the southeastern corner of East Baton Rouge Parish, Louisiana, an area known as St. George, wanted their own school district. They argued that the schools in East Baton Rouge were routinely named as among the lowest performing in the state, and were unlikely to improve any time soon. So, in 2012, some of those parents went to the state legislature with a proposal: Create what would be called the Southeast Community School District.

The legislature shot it down. The parents needed a two-thirds majority for the creation of a school district, and they couldn’t martial the votes. A similar push in 2013 was rebuffed as well.

The organizers were discouraged, but undeterred. They needed a new strategy—and they didn’t have to look far. In 2005, a nearby community, Central, was unable to gather support for a school district from the legislature, so it incorporated as a new city. That helped it gain legislative approval to create its own school district, Central Community Schools, which opened its doors in 2007. The St. George supporters launched a petition drive and, in August 2013, registered a new website: StGeorgeLouisiana.com. They would try to create their own city.

In 1996, a group of European researchers found that a certain gene, called SLC6A4, might influence a person’s risk of depression.

It was a blockbuster discovery at the time. The team found that a less active version of the gene was more common among 454 people who had mood disorders than in 570 who did not. In theory, anyone who had this particular gene variant could be at higher risk for depression, and that finding, they said, might help in diagnosing such disorders, assessing suicidal behavior, or even predicting a person’s response to antidepressants.

Back then, tools for sequencing DNA weren’t as cheap or powerful as they are today. When researchers wanted to work out which genes might affect a disease or trait, they made educated guesses, and picked likely “candidate genes.” For depression, SLC6A4 seemed like a great candidate: It’s responsible for getting a chemical called serotonin into brain cells, and serotonin had already been linked to mood and depression. Over two decades, this one gene inspired at least 450 research papers.

“I have been talking about China for many years. And you know what? Nobody listened,” Donald Trump told a crowd outside Pittsburgh in 2016. “But they are listening now.” If China’s leaders didn’t notice a campaign speech then, the president has their attention now.

In office, President Trump and his administration have taken a series of escalating measures against China in hopes they would coerce Beijing to change their trade practices. But, two years and numerous rounds of meetings later, the trade talks aren’t moving.

And now the Trump administration has dropped an economic bomb on China by taking steps to cut off tech giant Huawei from its American suppliers. The escalation points to an ominous reading of the trade war: It’s only the starting point for what administration hardliners see as a generational battle with America’s most powerful adversary since the Soviet Union.

The fight for control of information from the Russia investigation is heading into uncharted legal territory. The House Judiciary Committee has voted to hold Attorney General William Barr in contempt of Congress for his refusal to provide the committee with the full, unredacted version of Special Counsel Robert Mueller’s report. Earlier this month, House Intelligence Chairman Adam Schiff publicly signaled his intention to impose fines on the federal officials who refuse to comply with congressional subpoenas. “We’re looking through the history and studying the law to make sure we’re on solid ground,” the California Democrat said, revealing that he and his staff are aware that the move would be unorthodox and unconventional. Under these circumstances, the trepidations of the Democratic leadership are understandable. Yet the important thing is: Fining Barr would be legal—even if enforcing the fine could itself prove tricky.

To feel relief at my mother’s being dead was once unthinkable, but then the news came from Ireland. It would have crushed her. An immigrant’s daughter, my mother lived with an eye cast back to the old country, the land against which she measured every virtue. Ireland was heaven to her, and the Catholic Church was heaven’s choir. Then came the Ryan Report.

Not long before The Boston Globe began publishing its series on predator priests, in 2002—the “Spotlight” series that became a movie of the same name—the government of Ireland established a commission, ultimately chaired by Judge Sean Ryan, to investigate accounts and rumors of child abuse in Ireland’s residential institutions for children, nearly all of which were run by the Catholic Church.