America has botched its coronavirus response in so, so many ways since the pandemic began. Even in a country that stands apart from the world for its horrific failures, there have been as many leadership bungles as there are states: Some failed to heed early warnings. Others refused to learn the lessons of outbreaks that came before theirs. Still others played politics instead of following science. And then there’s Georgia.

Georgia’s response to the pandemic has not been going well. It was bad from the beginning: Back in early April, weeks after other states took initial precautions, Georgia dawdled toward a shutdown while its coronavirus cases surged. Still, less than a month later, the state chose to be among the first in the nation to reopen, bringing back businesses known to accelerate the virus’s spread, such as restaurants and gyms, even though new infections had never made a significant or sustained decline. In June, the state welcomed back bars. What happened next was predictable, and was predicted: Case counts came roaring back. More people got sick and died. Many of these deaths were preventable. The state now has the sixth-highest number of coronavirus cases in the United States, behind five states with significantly larger populations.

A few days before Donald Trump’s inauguration, then-National Security Adviser Susan Rice held a press briefing in her office to talk about the threats she saw on the horizon as Barack Obama’s presidency drew to a close. “What keeps you up at night? one reporter asked toward the end of the meeting. Her answer: a pandemic that spirals out of control.

Yesterday afternoon, I asked Rice how the past five months have compared to what she’d been worried about in the early days of 2017. “This is about in the realm of my worst nightmare,” she told me. That’s why, Rice said, she worked to put together plans, and why she oversaw the creation of the pandemic-preparedness office that Trump famously closed. “We knew it was going to happen. We just couldn’t know when.”

How did it come to this? A virus a thousand times smaller than a dust mote has humbled and humiliated the planet’s most powerful nation. America has failed to protect its people, leaving them with illness and financial ruin. It has lost its status as a global leader. It has careened between inaction and ineptitude. The breadth and magnitude of its errors are difficult, in the moment, to truly fathom.

In the first half of 2020, SARS‑CoV‑2—the new coronavirus behind the disease COVID‑19—infected 10  million people around the world and killed about half a million.

In March, tens of millions of American workers—mostly in white-collar industries such as tech, finance, and media—were thrust into a sudden, chaotic experiment in working from home. Four months later, the experiment isn’t close to ending. For many, the test run is looking more like the long run.

Google announced in July that its roughly 200,000 employees will continue to work from home until at least next summer. Mark Zuckerberg has said he expects half of Facebook’s workforce to be remote within the decade. Twitter has told staff they can stay home permanently.

With corporate giants welcoming far-flung workforces, real-estate markets in the superstar cities that combine high-paid work and high-cost housing are in turmoil. In the San Francisco Bay Area, rents are tumbling. In New York City, offices are still empty; so many well-heeled families with second homes have abandoned Manhattan that it’s causing headaches for the census.

From my parents’ teenage years in the 1930s and ’40s through my teenage years in the 1970s, American economic life became a lot more fair and democratic and secure than it had been when my grandparents were teenagers. But then all of a sudden, around 1980, that progress slowed, stopped, and in many ways reversed.

I didn’t really start understanding the nature and enormity of the change until the turn of this century, after the country had been fully transformed. One very cold morning just after Thanksgiving in 2006, I was on the way to Eppley Airfield in Omaha after my first visit to my hometown since both my parents had died, sharing a minivan jitney from a hotel with a couple of Central Casting airline pilots—tall, fit white men around my age, one wearing a leather jacket. We chatted. To my surprise, even shock, both of them spent the entire trip sputtering and whining—about being bait-and-switched when their employee-ownership shares of United Airlines had been evaporated by its recent bankruptcy, about the default of their pension plan, about their CEO’s recent 40 percent pay raise, about the company to which they’d devoted their entire careers but no longer trusted at all. In effect, about changing overnight from successful all-American middle-class professionals who’d worked hard and played by the rules into disrespected, cheated, sputtering, whining chumps.

The coronavirus that causes COVID-19 has sickened more than 16.5 million people across six continents. It is raging in countries that never contained the virus. It is resurging in many of the ones that did. If there was ever a time when this coronavirus could be contained, it has probably passed. One outcome is now looking almost certain: This virus is never going away.

The coronavirus is simply too widespread and too transmissible. The most likely scenario, experts say, is that the pandemic ends at some point—because enough people have been either infected or vaccinated—but the virus continues to circulate in lower levels around the globe. Cases will wax and wane over time. Outbreaks will pop up here and there. Even when a much-anticipated vaccine arrives, it is likely to only suppress but never completely eradicate the virus. (For context, consider that vaccines exist for more than a dozen human viruses but only one, smallpox, has ever been eradicated from the planet, and that took 15 years of immense global coordination.) We will probably be living with this virus for the rest of our lives.

Updated at 10:36 a.m. ET on August 5, 2020.

There’s a joke about immunology, which Jessica Metcalf of Princeton recently told me. An immunologist and a cardiologist are kidnapped. The kidnappers threaten to shoot one of them, but promise to spare whoever has made the greater contribution to humanity. The cardiologist says, “Well, I’ve identified drugs that have saved the lives of millions of people.” Impressed, the kidnappers turn to the immunologist. “What have you done?” they ask. The immunologist says, “The thing is, the immune system is very complicated …” And the cardiologist says, “Just shoot me now.”

The thing is, the immune system is very complicated. Arguably the most complex part of the human body outside the brain, it’s an absurdly intricate network of cells and molecules that protect us from dangerous viruses and other microbes. These components summon, amplify, rile, calm, and transform one another: Picture a thousand Rube Goldberg machines, some of which are aggressively smashing things to pieces. Now imagine that their components are labeled with what looks like a string of highly secure passwords: CD8+, IL-1β, IFN-γ. Immunology confuses even biology professors who aren’t immunologists—hence Metcalf’s joke.

Famous people want the world to know that Ellen DeGeneres is nice to famous people. Addressing media reports alleging a culture of harassment and bullying at DeGeneres’s talk show, the singer Katy Perry tweeted Tuesday that she’s “only ever had positive takeaways from my time with Ellen.” Ashton Kutcher, Kevin Hart, Jay Leno, Diane Keaton, and the superstar agent Scooter Braun have all recently made similar declarations about DeGeneres’s kindness, so as to push back against claims painting her as callous toward staffers, fans, and other entertainment-industry figures. “Looking forward to the future where we get back to loving one another,” Hart wrote, blasting those who have criticized DeGeneres and called for her to step down. “This hate shit has to stop.”

Despite the continued spread of the coronavirus, many colleges around the country plan to welcome students back to campus over the coming weeks.

Colleges want to reopen for good, nontrivial reasons. Administrators believe that most students learn better when they are physically assembled in the same place. And they know that the American college experience, at any rate, has long been about more than the classroom. It allows students to cut the umbilical cord, make friends with like-minded people, and pursue extracurricular activities—all of which are much harder to do if your freshman year consists of joining Zoom sessions from your parents’ basement. Many universities also face serious financial problems. If they are unable to reopen this fall, some may collapse.

While much of Europe and Asia has relaxed lockdown measures after overcoming the pandemic’s first wave, the United States has moved firmly into its second surge. With more than 4 million confirmed coronavirus cases and upwards of 150,000 deaths, the country that was supposed to be the most prepared to handle a public-health crisis is proving itself to be among the worst at it.

To focus solely on the U.S., however, would be to miss the even more alarming situation occurring in much of the developing world. Brazil, second only to the U.S. in confirmed cases and deaths, has recorded more than 2 million infections. India, the world’s second-most populous country with the third-highest number of cases, is approaching the same grim milestone. Similar increases are occurring in South Africa, Mexico, Peru, Chile, and Colombia. Taken collectively, these countries account for more than a third of the world’s confirmed infections. And such figures only reflect the cases we know about.