Nick Gillespie and Matt Welch make the case:

Though limited to voters in a single state, Prop. 19 is the only policy matter on the table with the potential to restructure the lives of virtually all Americans. If Prop. 19 passes, it will force, at long bloody last, an honest reconsideration of failed prohibitionist policies throughout the United States. In fact, given the drug war's influence on our foreign policy in Latin America and central Asia, Prop. 19's reverberations would even be felt far outside our borders.

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