Alcohol doesn't take full effect until long after it is ingested. A study tests whether inexperienced drinkers have a hard time gauging how much alcohol is too much. Yep:

[T]he folk advice to never go out drinking on an empty stomach may not be so wise after all. It's sensible for people who intend to drink a fixed amount but not for people intending to drink until they reach a desired level of inebriation. "Here we show that it may not be sound advice for inexperienced juveniles that drink according to a simple feedback strategy," the researchers said. "Drinking on a full stomach massively extends the stomach delay, thereby making it much harder to manage one's blood alcohol level."

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