Adrianne Palicki
Charming, talented, and crazy gorgeous, Palicki breathed incredible life into Tyra Collette, the wrong-side-of-the-tracks girl with secret smarts and tenacity. She seemed destined for great things when she ended her run on Friday Night Lights, but then came her next project, another Texas-set drama called Lone Star, which was quickly canceled despite critical approval. She had a role in the Red Dawn remake that was shelved for ages, and of course there was David E. Kelley's scuttled Wonder Woman pilot which never saw the light of day, though unfortunately some embarrassing set photos did. Palicki, who was in G.I. Joe: Retaliation this year, has a couple of upcoming projects listed on her IMDb, among them a thriller with Keanu Reeves, but we fear that this eminently likable actress may have been permanently hobbled by whatever poltergeist is plaguing the FNL kids.
Zach Gilford
Gilford made many FNL fans swoon playing huggable-cute boyfriend-next-door Matt Saracen, though he also showed plenty of weighty seriousness in episodes like "The Son." Sadly, things have not been good for Gilford in recent years. Both of his attempts at new series, Off the Map and Mob Doctor, were quickly canceled flops, and the 2010 pilot Matadors, a modern version of Romeo & Juliet, never made it to air. On the big screen, Gilford has appeared in a string of forgettable B-movies and that's about it. What's wrong with this world, when someone as lovable as Matt Saracen can't find decent work in Hollywood? This can only be the work of some dark force.
Minka Kelly
When not grabbing headlines for bad airplane behavior, Kelly, who played soulful teen queen Lyla Garrity on FNL, has spent her post-Dillon years doing junky stuff with a few respectable gigs here and there. She appeared on several episodes of the much-adored Parenthood, before doing a short stint on the reviled and swiftly axed Charlie's Angels reboot. She made a blink-and-you-missed-it appearance in The Butler, as Jackie Kennedy, and is now set to appear on Almost Human, a hokey and not terribly engaging sci-fi yarn in which she rather unconvincingly plays a cop. So, it's been a mixed bag. But the fact that she dated Derek Jeter, a Yankee of all things, really proves that some curse is at work.
Scott Porter
This is where things start to turn a corner. After he ended his run as Jason Street on Friday Night Lights, Porter did an arc on CBS's excellent The Good Wife and appeared in the likable high school reunion indie 10 Years. He's now gainfully, if not terribly fruitfully, employed on The CW's Hart of Dixie, playing the occasional love interest of Rachel Bilson's character. So, he's working, but... y'know.
Gaius Charles
After two seasons of playing star running back Smash Williams, Charles went on to do a few episodes of another show about football, Necessary Roughness, before landing a good gig on Grey's Anatomy, where he's been since last year. So, not bad, but not great. Grey's Anatomy has been on forever! Not a terrific place from which to launch a campaign for true stardom.