MSNBC's Mark Murray points out that conservatives are talking about it. That would mean Marco Rubio running to get elected just four years removed from his time in the Florida legislature, where he served as Speaker. But hey, if he wins his Senate race, his story wouldn't be all that different from President Obama's....the president was elected to Illinois' state Senate in 1996 and served until 2004, when he got elected to the U.S. Senate, then was elected president four years later.
Rubio, if successful this November, would have served a similar term (2000-2008) in the Florida state House, then two years as senator before his presidential election year.
Differences: Obama ran an unsuccessful U.S. House campaign in the interim; Rubio served as state House Speaker.
More likely, Rubio could broker some conservative power with his endorsement in 2012, or maybe get on the ballot as a VP.