Anurag Mairal, director of technology solutions at PATH Health Technologies, says that it's time to start looking at low-cost innovations in healthcare differently. What should the road map be for an innovation? Should the product debut in a developing country first and then, evolve for the developed market or vice versa?
"We're at a point now, that companies cannot just keep adding bells and whistles to the same product to garner sales," Mairal told me.
So, given the increasing costs of healthcare in the U.S. and in Europe, companies are looking increasingly at simpler solutions that have the capacity to criss-cross border with a few tweaks.
PATH is a Seattle-based non-profit. But it's working with the commercial sector to scale, distribute, and market its innovations. That's Mairal's task. He's a new addition to the PATH team, after a noted career with Johnson & Johnson companies. He is symbolic of this merger between social impact and commercial viability.
His approach includes disruptive innovation (disrupt the global health system by changing the cost equation, moving away from a grants-based approach to a commercial-approach) and developing a market for said innovations. It's not enough to innovate. Must build a system to introduce these innovations to the market, advertise them, create distribution chains, and get them to the end-user.
PATH was started in the 1970s by three researchers: Gordon Duncan, Rich Mahoney, and Gordon Perkin. Their aim was quite the same: bring together public health and the private sector. Their focus, though, was slightly different: population control. So, their first innovations addressed population overload -- interventions to curb birth rates -- and were focused on Asia.
Since then, they've expanded their focus, looking at nutrition, water, sanitation, vaccinations, and reproductive health. Here are some of the innovations that PATH has piloted:
River blindness tests
It looks like a pregnancy test but it's designed to identify river blindness (or a tropical disease, "onchocerciasis"), which is a preventable condition that has affected 37 million people globally, many in poor, rural communities situated near a water source. With a grant from the Gates Foundation for $1.8 million, PATH created this device. Traditionally, a health worker would have have to draw a vial blood, take it to a clinic where it can be processed, and then report the results several days later. The later strip, however, requires just one drop of blood from a finger prick and results are available in 20 minutes. Ideal for rural health workers.
Rice is a popular grain, eaten by half the world's population. Fortified rice includes micronutrients such as iron, thiamin, zinc, vitamin A, and folic acid. PATH partnered with food purveyors in India, Brazil, and Colombia to produce the fortified grains to combat iron deficiencies, malnourishment, and anemia. Now, the grains are being coupled with school meal programs, such as in Burundi, to ensure that they reach school kids in low-income communities.
Mobile-phone milk pasteurization
Still in the works, FoneAstra is a system that uses mobile phones to monitor flash-heat pasteurization of donor breast milk. When a mother's milk is not safe to consume or is simply not available, human milk banks (HMB) fill the need; WHO supports the use of HMBs to address malnourished infants. However, the pasteurization process is tricky and healthcare facilities are hesitant to use this donor milk, unsure of its safety. By having a cell phone attached to the pasteurization device, FoneAstra enables these health clinics to monitor data on pasteurization, assuring them that the milk is safe to use. A pilot is under way in South Africa with the Human Milk Banking Association.
PATH created this design after consulting with women globally (in the US, South Africa, Thailand, and Dominican Republic) to ensure that they had single-size solution. It's more "discreet" than the condom, is easier to use than hormonal contraception, and enables women to protect themselves from unwanted pregnancy and some sexually-transmitted diseases. Now, PATH is commercializing this for sale with Germany-based health company, Kessel. But, it's also trying to figure out how the diaphragm could be integrated into family planning programs, given that it's a reusable product and would eliminate trips to a local health clinic. Those projects are under way in Uganda, India, and South Africa.
Vaccine vial monitors
Vaccine temperatures are critical - if too hot, they lose their potency. One of PATH's earliest innovations (1996) included the vaccine vial monitor- a square indicator on the label that lets health workers know if the vaccine is still safe to use. Modeled after a technology used in the food industry, it prevented WHO from dumping massive quantities of vaccines whose potency would be "unknown" after a day in the sun or in the hands of a health worker. UNICEF and WHO claim that this innovation saves the global health community $5 million every year.
The opposite problem of vaccines getting too hot -- they freeze in the carriers. Coupled with ice packs, the vaccines can be at the risk of freezing which diminish their potency as well. Solution? PATH discovered a new way to use nontoxic, biodegradable phase-change material with ice packs to prevent freezing.
Here's a product that debuted in the developed world but is being refined, and considered for the developing world as well. While you can find a female condom in drug stores, Mairal explains that they're not popular. Why? They're not always easy to use and can be uncomfortable. A more refined version, developed by PATH, has higher quality materials (i.e. 0.03 mm thin polyurathane film that allows for heat transfer), claims to be easier to use and feels more natural.
Rather than showcasing pre-made videos on maternal and neonatal health, PATH's Digital Public Health Platform -- basically, video and projector equipment- is enabling rural women in Rajasthan, India to create videos, showcase their films, and answer questions. The community-driven approach includes teams of health workers for local solutions and storytelling.
As government agencies and tech companies develop more and more intrusive means of watching and influencing people, how can we live free lives?
I knew we’d bought walnuts at the store that week, and I wanted to add some to my oatmeal. I called to my wife and asked her where she’d put them. She was washing her face in the bathroom, running the faucet, and must not have heard me—she didn’t answer. I found the bag of nuts without her help and stirred a handful into my bowl. My phone was charging on the counter. Bored, I picked it up to check the app that wirelessly grabs data from the fitness band I’d started wearing a month earlier. I saw that I’d slept for almost eight hours the night before but had gotten a mere two hours of “deep sleep.” I saw that I’d reached exactly 30 percent of my day’s goal of 13,000 steps. And then I noticed a message in a small window reserved for miscellaneous health tips. “Walnuts,” it read. It told me to eat more walnuts.
Astronomers have spotted a strange mess of objects whirling around a distant star. Scientists who search for extraterrestrial civilizations are scrambling to get a closer look.
In the Northern hemisphere’s sky, hovering above the Milky Way, there are two constellations—Cygnus the swan, her wings outstretched in full flight, and Lyra, the harp that accompanied poetry in ancient Greece, from which we take our word “lyric.”
Between these constellations sits an unusual star, invisible to the naked eye, but visible to the Kepler Space Telescope, which stared at it for more than four years, beginning in 2009.
“We’d never seen anything like this star,” says Tabetha Boyajian, a postdoc at Yale. “It was really weird. We thought it might be bad data or movement on the spacecraft, but everything checked out.”
Kepler was looking for tiny dips in the light emitted by this star. Indeed, it was looking for these dips in more than 150,000 stars, simultaneously, because these dips are often shadows cast by transiting planets. Especially when they repeat, periodically, as you’d expect if they were caused by orbiting objects.
A decade since the book pushed “pickup artistry” into the mainstream, Neil Strauss has some mixed thoughts on its legacy.
When Neil Strauss’s blockbuster book about pickup artistry came out a decade ago, I was a Midwestern ingenue in New York City, and I read it mostly as a defensive measure. A nice Ph.D. student named Jon had mentioned The Game, and was demonstrating how it worked by means of “The Cube” routine, where you ask a woman to imagine a box standing in the desert, and you tell her about herself based on how she describes it. (The cube represents the woman’s ego or something—so if it’s big, it means she’s self-confident; if it’s transparent as opposed to opaque that means she’s open as opposed to guarded; if it’s pink that means she’s bright and energetic … basic non-falsifiable horoscope-type material she can read herself into and then find you perceptive.) It was basically a way to harness people’s love of talking about themselves in order to score.
Bill Gates has committed his fortune to moving the world beyond fossil fuels and mitigating climate change.
In his offices overlooking Lake Washington, just east of Seattle, Bill Gates grabbed a legal pad recently and began covering it in his left-handed scrawl. He scribbled arrows by each margin of the pad, both pointing inward. The arrow near the left margin, he said, represented how governments worldwide could stimulate ingenuity to combat climate change by dramatically increasing spending on research and development. “The push is the R&D,” he said, before indicating the arrow on the right. “The pull is the carbon tax.” Between the arrows he sketched boxes to represent areas, such as deployment of new technology, where, he argued, private investors should foot the bill. He has pledged to commit $2 billion himself.
Is there anything inherently “doggy” about the word “dog”? Obviously not—to the French, a dog is a chien, to Russians a sobaka, to Mandarin Chinese-speakers a gǒu. These words have nothing in common, and none seem any more connected to the canine essence than any other. One runs up against that wall with pretty much any word.
Except some. The word for “mother” seems often either to be mama or have a nasal sound similar to m, like nana. The word for “father” seems often either to be papa or have a sound similar to p, like b, in it—such that you get something like baba. The word for “dad” may also have either d or t, which is a variation on saying d, just as p is on b. People say mama or nana, and then papa, baba, dada, or tata,worldwide.
When “M.S.” was 13, her math teacher at Edison middle school in Los Angeles invited her to be friends online. Soon, according to a California appeals court, the same teacher started sending her sexually explicit messages. That winter, he called the 8th grader into a classroom and told her to shut the door. The teacher, Elkis Hermida, kissed and hugged the student. In March, he drove M.S. (as she’s referred to in court records, to protect her privacy), then 14, to a motel, where, according to the court, “they had sexual intercourse.” On a second occasion, they “had sexual intercourse” in Hermida’s classroom.
“The next time they had sexual intercourse was on a Saturday at a motel,” the court records say. “Hermida told her that they were not in a relationship but were just having sex.” At that point, M.S. “wanted to stop having sexual intercourse with Hermida, but did not feel that she was free to do so.” At their next encounter, the teacher wanted anal sex. M.S. objected. “Hermida inserted something into her anus anyway,” the court said.
When a congressional investigation turns into a partisan operation, the media need to treat it as such.
Hardly anyone still working in today’s media can remember an era in which “mainstream media” practices, as we now think of them, actually prevailed. By which I mean: a few dominant, sober-sided media outlets; a news cycle punctuated by evening network-news shows, morning (and sometimes afternoon) newspapers, weekend newsmaker talk shows, and weekly news magazines; and political discourse that shared enough assumptions about facts and logic that journalists felt they could do their jobs by saying, “We’ve heard from one side. Now let’s hear from the other.”
I can barely remember any of that, and I got my first magazine job (with The Washington Monthly) around the time of the Watergate break-in and subsequent Woodward-and-Bernstein scoops, when all parts of the old-style journalistic ecosystem were still functioning.
Before it became the New World, the Western Hemisphere was vastly more populous and sophisticated than has been thought—an altogether more salubrious place to live at the time than, say, Europe. New evidence of both the extent of the population and its agricultural advancement leads to a remarkable conjecture: the Amazon rain forest may be largely a human artifact
The plane took off in weather that was surprisingly cool for north-central Bolivia and flew east, toward the Brazilian border. In a few minutes the roads and houses disappeared, and the only evidence of human settlement was the cattle scattered over the savannah like jimmies on ice cream. Then they, too, disappeared. By that time the archaeologists had their cameras out and were clicking away in delight.
Below us was the Beni, a Bolivian province about the size of Illinois and Indiana put together, and nearly as flat. For almost half the year rain and snowmelt from the mountains to the south and west cover the land with an irregular, slowly moving skin of water that eventually ends up in the province's northern rivers, which are sub-subtributaries of the Amazon. The rest of the year the water dries up and the bright-green vastness turns into something that resembles a desert. This peculiar, remote, watery plain was what had drawn the researchers' attention, and not just because it was one of the few places on earth inhabited by people who might never have seen Westerners with cameras.
When the Sony hack happened and I found out how much less I was being paid than the lucky people with dicks, I didn’t get mad at Sony. I got mad at myself. I failed as a negotiator because I gave up early. I didn’t want to keep fighting over millions of dollars that, frankly, due to two franchises, I don’t need. (I told you it wasn’t relatable, don’t hate me).
Science says lasting relationships come down to—you guessed it—kindness and generosity.
Every day in June, the most popular wedding month of the year, about 13,000 American couples will say “I do,” committing to a lifelong relationship that will be full of friendship, joy, and love that will carry them forward to their final days on this earth.
Except, of course, it doesn’t work out that way for most people. The majority of marriages fail, either ending in divorce and separation or devolving into bitterness and dysfunction. Of all the people who get married, only three in ten remain in healthy, happy marriages, as psychologist Ty Tashiro points out in his book The Science of Happily Ever After, which was published earlier this year.
Social scientists first started studying marriages by observing them in action in the 1970s in response to a crisis: Married couples were divorcing at unprecedented rates. Worried about the impact these divorces would have on the children of the broken marriages, psychologists decided to cast their scientific net on couples, bringing them into the lab to observe them and determine what the ingredients of a healthy, lasting relationship were. Was each unhappy family unhappy in its own way, as Tolstoy claimed, or did the miserable marriages all share something toxic in common?