Via Vulture, I see that Two And A Half Men is chugging along:
Sources tell The Hollywood Reporter that series co-creator Chuck Lorre has hatched an idea to reboot the Warner Bros.-produced sitcom with a new creative direction that does not involve Sheen, who was fired from the series in March. Lorre is said to have presented close associates and Men co-star Jon Cryer with the plan, and the studio and network are aware of his intentions. According to an insider, Lorre has told Cryer this reboot would involve a significant role for him and the introduction of a new, yet-to-be-cast character.
This isn't surprising, but I'm always wondering in how much a show is driven by its star, and how much it's driven by a formula. Obviously, it will different for each show. I never watched Two and a Half Men, so I can't judge what Sheen brought to the role. Still, I'll be interested in how this goes.