Its an old debate, but Derek Lowe links to some suggestive new evidence. It's far from conclusive, but confirms my decision to start trying to limit my exposure to the stuff. Hopefully, it will also inspire Americans to limit their exposure to noxious sugar subsidies, which keep the price of sugar artificially high, and thus encourage food processors to use more HFCS. If anything can overcome the evil twins of ADM and the sugar lobby, it might just be America's neurotic fear of fat.
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